Conclusion The consecutive chemotherapy can decrease the infection rate and the mean EPG of the hookworm infection rapidly and keep them at lower level. 结论连续选择性化疗可使钩虫病流行区的感染率和感染度迅速下降,并维持在较低水平。
High protection was reached with worm reduction rate of 99% by the regimens of 300 mg/ kg once a week for 4 consecutive weeks beginning 14d after infection. 小鼠感染14d后每周口服1次青蒿琥酯300mg/kg,连续4wk,减虫率达99%;